Penicillin / Streptomycin / Amphotericin Solution

The Penicillin / Streptomycin / Amphotericin Solution is a comprehensive antimicrobial formulation designed to safeguard mammalian cell cultures from microbial contamination. It combines Penicillin G, which is effective against Gram-positive bacteria, Streptomycin, which targets Gram-negative bacteria, and Amphotericin B, which provides protection against fungi and yeasts. Together, these components deliver enhanced coverage compared to standard Pen/Strep mixtures, offering reliable protection in sensitive or long-term culture systems.

This sterile, ready-to-use solution can be conveniently added to culture media at the recommended working concentration. It helps preserve the integrity of cell culture experiments by maintaining aseptic conditions without interfering with cell health or experimental outcomes. The solution is widely used in cancer biology, immunology, virology, toxicology, and biopharmaceutical research where contamination control is essential.

By combining antibacterial and antifungal activity, the Penicillin / Streptomycin / Amphotericin Solution provides researchers with an effective safeguard to ensure consistent, reproducible, and contamination-free results in both routine and advanced cell culture workflows.

Application:

Penicillin-Streptomycin-Amphotericin (Pen/Strep/Amph) is a widely used antibiotic mixture in cell culture to prevent or control bacterial contamination.

Background:

The Antibiotic Mixture is used in Cell Culture for its Broad Spectrum Activity, Convenient Format, Prevention of Contamination and as a Short Term Rescue Tool. It covers both Gram-positive and Gram-negative bacterial species commonly encountered in lab environments.

Disclaimer:

The data indicated herein are as indicated and validated in our laboratory. As these cell lines are of human origin, they carry a risk of latent human viruses (e.g., Epstein-Barr virus, hepatitis B). Therefore they should be handled accordingly with precaution. These reagents are for research use only and not for in-vitro diagnostics or human use.